Medical Degree Program in China - Oral Mucosal Disease

1. Introduction
 
Oral Mucosal Disease generally refers to the oral cavity ulcer. Oral ulcer, commonly known as "Aphtha", is a common ulcer injury symptom occurring on oral mucosas, which is common in the following parts: medial lip, tongue, ventral tongue, buccal mucosa, vestibule, soft palate, etc., the mucous membrane of these parts of lacks of horny layer or the keratinized is poor. Ulcer of the tongue refers to the mouth ulcer occurring in the tongue and the abdominal part of the tongue. Oral ulcer has acute ache, local burning pain is obvious, serious patients will be affected in eating, talking, causing great inconvenience to daily life; concurrent symptoms include bad breath, chronic pharyngitis, constipation, headache, dizziness, nausea, fatigue, irritability, fever, swollen lymph nodes and other systemic symptoms.
 
2. Etiology
 
The occurrence of oral ulcer is the result of a variety of factors, including local trauma, mental stress, food, drugs, malnutrition, hormone levels and lack of vitamins or trace elements. Systemic disease, heredity, immunity and microorganism may play an important role in the occurrence and development of oral ulcer. Such as the lack of trace elements of zinc, iron, lack of folic acid, vitamin B12 and malnutrition etc., decreased immune function increase the possibility of oral ulcer; Streptococcus, streptococcus sanguis and helicobacter pylori bacteria are closely related with oral ulcer. Oral ulcers usually indicates that the body may have an underlying systemic disease, oral ulcer is closely related with gastric ulcer, duodenal ulcer, ulcerative colitis, limitations enteritis, hepatitis, B vitamins absorption disorders, plant nerve function disorder, etc.
 
3. Clinical Manifestations
 
There is a variety of ulcer and damage diseases of oral mucosa, for example:
(1) Recurrent aphthous stomatitis
(2) Behcet syndrome
(3) Traumatic ulcer
(4) Carcinelcosis
(5) Herpes simplex
(6) Radioactive stomatitis
(7) Tuberculosis ulcer
(8) Necrosis of the salivary glands
 
4. Principle of Treatment
 
For the treatment of oral ulcer, the main method is to eliminate the pathogeny, enhance physique, symptomatic treatment; the treatment should adhere to the combination of systemic therapy and local treatment, combination of traditional Chinese and Western medicine treatment, combination of physiological and psychological treatment. Attention should be paid to large and deep tongue ulcers which cannot be healed for a long time, these tongue ulcers may be precancerous lesions, which are easy to be canceration; a biopsy should be taken for a definite diagnosis when necessary.
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Anhui Medical University

Wenzhou Medical University

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